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I am 49 years old, my mother is in hospital with 2 knee replacement and I have noticed over the years I too have pain in my knees after years of then cracking as I walked upstairs. Then the pain got worse so I went to the doc and he told me to try Celebrex 300 mg a day and let me tell you so far no side effects and I am happy again. The wife says I am acting strange, she's never seen me so happy but its not for all. For me I wish I would have done this a lot sooner.
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Have been taking about 3 weeks (200mg/daily). Started having irregular heartbeats after about 2 weeks. Stopped taking and it cleared up, I started taking again and irregular heartbeats have returned. I guess I will have to stop, what a shame--- it really helps the pain!!!

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The COX-2 selective NSAIDs examined were found to be similar to non-selective NSAIDs for the symptomatic relief of RA and OA and to provide superior GI tolerability (the majority of evidence is in patients with OA).

When the body breaks down purines, it produces uric acid, and excess uric acid causes painful crystals to deposit in the joints.

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After excluding the studies with poor methodological quality, the results did not change significantly.

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CBT is effective at reducing the symptoms of fatigue, and it appears to be more effective than other psychological therapies.

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